Aftereffects of cerebral infarction / strokeAftereffects of cerebral infarction / strokeAftereffects of cerebral infarction / stroke | Smart Clinic Tokyo[Official] | Regenerative Medicine (SHED-CM therapy, conditioned medium of stem cells from human exfoliated deciduous teeth (SHED-CM)) Tokyo’s Ichigaya, Yotsuya, and Kojimachi Stations


At Smart Clinic Tokyo, we are actively using SHED-CM therapy with conditioned medium of stem cells from human exfoliated deciduous teeth (SHED-CM) to treat incurable diseases (also known as unmet medical needs).Here, we will introduce the types of diseases, therapy outlines and prices that we can provide at our Clinic.

Aftereffects of cerebral infarction / stroke

Description of disease

Stroke symptoms can be broadly classified into three types: cerebral infarction caused by a clogged cerebral blood vessel, cerebral hemorrhage caused by a rupture of a small blood vessel in the brain resulting in a hematoma in the brain, and a subarachnoid hemorrhage caused by a ruptured cerebral aneurysm in the subarachnoid space.
Once a cerebral infarction occurs, cranial nerves in that area are damaged. The aftereffects will depend on the function of the damaged area. Typical symptoms may range from mild symptoms such as sensory or motor paralysis on one side of the body and loss of fine control of limbs through to severe symptoms including loss of use of limbs. This has a wide range of symptoms, which can include loss of physical balance, dizziness, dysarthria, impaired thinking, memory, and learning, and in some cases, difficulty in controlling emotions, personality changes, and psychiatric symptoms.

Therapy and administration

SHED-CM therapy (nasal drops)
·SHED-CM is delivered to the cranial nerves via nasal drops. This therapy method is expected to regenerate damaged nerve cells in the brain, leading to an improvement in symptoms*. Nasal drops are administered by a doctor at the first visit, and then you are prescribed a month's supply of the nasal drops. With these, you can administer the therapy every day by yourself.
*Inoue, T., Sugiyama, M., Hattori, H., Wakita, H., Wakabayashi, T., and Ueda, M.(2013). Stem cells from human exfoliated deciduous tooth-derived conditioned medium enhance recovery of focal cerebral ischemia in rats. Tissue Eng. Part A 19, 24–29. doi: 10.1089/ten.TEA.2011.0385

Therapy details

Consultation, blood test

Therapy duration

We will offer a therapy plan and duration to best suit the patient's symptoms.

Possible side effects

·Allergic reactions (itching, rash)
·Hyper-reactivity (headaches, irritation)

Reference fee

First visit 99,000 to 150,000 yen
*Additional fees to the above may be charged depending on the details of the consultation and its therapies .
*Not covered by health insurance